Recruitment of a splicing factor to the nuclear lamina for its inactivation

HIGHLIGHTS

• who: Karen Vester from the Institut Science University have published the paper: Recruitment of a splicing factor to the nuclear lamina for its inactivation, in the Journal: (JOURNAL)
• what: The authors present an approach that allows the fast and reversible recruitment of splicing factors to selected nuclear regions via reversible chemically induced dimerization (rCID). The authors show that fusion of the FKBP domain to a target splicing factor and concomitant fusion of the SNAP-tag to an anchor protein that exhibits a defined sub-nuclear localization allows for the recruitment of the splicing factor to . . .
  

   

  

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