HIGHLIGHTS
- who: Lukas Möller from the Institute of Biology, ETH Zurich, Zurich, SwitzerlandUniversity of have published the research: Recursive Editing improves homology-directed repair through retargeting of undesired outcomes, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- what: The authors demonstrate that Recursive Editing is an effective strategy to increase HDR efficiency. Utilizing outputs from REtarget, the authors demonstrate HDR enhancement by Recursive Editing at numerous sites, in diverse cell types, and with distinct genomic modifications.
- future: Advances in the accuracy and breadth of gRNA efficacy prediction could be easily incorporated into future versions . . .
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