Redd1 promotes obesity-induced metabolic dysfunction via atypical nf-κb activation

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  • who: Dong-Keon Lee from the Mouse models All mouse experiments were approved by the Animal Ethics Committee of Kangwon National University (approval numbers KW-190425-5, KW-190723-1, KW-190819-1, and KW-190819-1)All experiments were conducted adhering to the NIH Guide for the Care and Use of Laboratory Animals. Male C BL/6, ob/ob, and db/db mice were obtained from Orient Bio Inc. (Sungnam, South Korea). Redd1+/- mice were bred and maintained in the animal facility at Kangwon National University and intercrossed to obtain Redd1-/- and WT littermates as previously . . .

     

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