Redefining germline predisposition in children with molecularly characterized ependymoma: a population-based 20-year cohort

HIGHLIGHTS

  • who: Jon Foss-Skiftesvik from the Department of Neurosurgery, Section, Rigshospitalet University Hospital, Inge Lehmanns Vej, Copenhagen, Denmark have published the paper: Redefining germline predisposition in children with molecularly characterized ependymoma: a population-based 20-year cohort, in the Journal: (JOURNAL)
  • what: The etiology is largely unknown and DNA sequencing studies focusing on childhood ependymoma are limited. The aim of this population-based study was to investigate genetic predisposition in children with molecularly classified ependymoma due to rare pathogenic germline variants both in and outside known cancer genes.
  • future: As no single gene . . .

     

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