HIGHLIGHTS
- who: Barbara Marengo et al. from the Department University of Genova, Genova, Italy have published the Article: Redox Homeostasis and Cellular Antioxidant Systems: Crucial Players in Cancer Growth and Therapy, in the Journal: (JOURNAL)
- what: Cancer cells with high levels of Nrf2 have been shown to be less sensitive to etoposide, cisplatin, and doxorubicin and the studies demonstrated that activation of Nrf2 and of its target genes plays a key role in the resistance of neuroblastoma cells to GSH depletion or proteasome inhibition . The studies have demonstrated that BSO-induced ROS overproduction and apoptosis of . . .
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