HIGHLIGHTS
- who: Jelle Ameele from the Gurdon Institute University of have published the paper: Reduced chromatin accessibility correlates with resistance to Notch activation, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- how: All mouse husbandry and experiments were carried out in a Home Office-designated facility according to the UK Home Office guidelines upon approval by the local ethics committee (project licence PPL70/8727).
- future: With recent advances in single-cell technology future experiments may be able to better characterize variability in NOTCH activity within cell populations in the developing cortex.
SUMMARY
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