HIGHLIGHTS
- who: R ESEAR CH AR and colleagues from the Patients and controls This study complied with all relevant national regulations, institutional policies and was in accordance with the tenets of the Helsinki Declaration (as revised in, ) and has been approved by the Ethics Committee of the Second Hospital of Jilin University (IRB No26/06/, on, .06.2017). Written informed consents were obtained from all individuals included in this study. The sample size numbers were calculated by Clinical Research Sample Size Calculator. Fifty-one PBC patients and , sex- and age-matched healthy individuals were included between July , and . . .
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