Reduced diversity of intestinal t-cell receptor repertoire in patients with crohn’s disease

HIGHLIGHTS

• who: Sung Noh Hong from the Aalborg University, Denmark have published the research work: Reduced diversity of intestinal T-cell receptor repertoire in patients with Crohnu2019s disease, in the Journal: (JOURNAL)
• what: This study demonstrated that the expression pattern of the TCR repertoire differs between the intestinal mucosa in patients with CD and non-IBD controls. The authors focused on TCR repertoires of the inflammation site regardless of whether the samples were from the colon or ileum.
• how: These results indicated that the richness of clonotypes did not differ whereas the diversity of . . .
  

   

  

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