Reduced dopamine signaling impacts pyramidal neuron excitability in mouse motor cortex

HIGHLIGHTS

• who: Significance Statement and collaborators from the Department of Neurobiology and Behavior, Stony Brook University, Stony Brook, New York , and Graduate have published the research work: Reduced Dopamine Signaling Impacts Pyramidal Neuron Excitability in Mouse Motor Cortex, in the Journal: (JOURNAL) of September/23,/2021
• what: The authors show that D1 receptor (D1R) and D2R antagonism altered subthreshold and suprathreshold properties of M1 neurons in a layer-specific fashion. Recorded neurons included in this study showed pyramidal morphology and were negative for GAD67 immunoreactivity (Fig 1B). Next, the authors assess the effect of D1R blockade . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.