Reduced expression of the rock inhibitor rnd3 is associated with increased invasiveness and metastatic potential in mesenchymal tumor cells

HIGHLIGHTS

• who: Cristina Belgiovine et al. from the Dipartimento di Genetica e Microbiologia, Università di Pavia, Pavia, ItalyEditor: Neil AHotchin, University of Birmingham, United Kingdom have published the research: Reduced Expression of the ROCK Inhibitor Rnd3 Is Associated with Increased Invasiveness and Metastatic Potential in Mesenchymal Tumor Cells, in the Journal: (JOURNAL) of November/30,/2010
• what: The authors have exploited the cen3tel model of isogenic cells at different stages of transformation, from normal fibroblasts up to metastatic cells, to study changes in the migratory and invasive potential accompanying human fibroblast neoplastic transformation. The authors show . . .
  

   

  

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