Reduced gaba content in the motor thalamus during effective deep brain stimulation of the subthalamic nucleus

HIGHLIGHTS

  • who: Alessandro Stefani from the Istituto di Ricovero e Cura a Carattere Scientifico, Fondazione SLucia, Roma, Italy University of Mexico, Mexico have published the Article: Reduced GABA content in the motor thalamus during effective deep brain stimulation of the subthalamic nucleus, in the Journal: (JOURNAL)
  • what: The authors demonstrate that, whatever is the final modulation in cortex GABA decline in the motor thalamus is central for the clinical amelioration but that the latter may associate (under DBS) or not (under LD, Stefani et_al, 2011) with changes of GPi cGMP (a marker of STN-pallidal excitability . . .

     

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