HIGHLIGHTS
- who: Guoliang Zhang from the (UNIVERSITY) have published the article: Reduced hyaluronan cross-linking induces breast cancer malignancy in a CAF-dependent manner, in the Journal: (JOURNAL)
- what: Given the protective role of cross-linked HA in physiological and inflammatory processes, the authors propose that HA cross-linking might become deficient during tumor malignancy. Next, the authors determine whether TSG6 contributes to the deficiency of cross-linked HA in breast cancer. The experiment found that NFbs and CAFs with different levels of crosslinked HA were obtained through regulating TSG6 expression, whereas the quantities and MW . . .
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