Reducing ether lipids improves drosophila overnutrition-associated pathophysiology phenotypes via a switch from lipid storage to beta-oxidation

HIGHLIGHTS

  • who: Christie Santoro from the DepartmentBinghamton University have published the research work: Reducing ether lipids improves Drosophila overnutrition-associated pathophysiology phenotypes via a switch from lipid storage to beta-oxidation, in the Journal: Scientific Reports Scientific Reports
  • what: This approach showed that HS + DHAPATi flies had an increased metabolic rate when compared to HS controls (Fig 5A). The authors used HS-fed Drosophila to explore the role of the ether lipid biosynthesis gene, DHAPAT, in obesity-associated pathophysiology phenotypes.
  • how: Because these organs are small and the authors chose a timepoint where pathophysiology . . .

     

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