HIGHLIGHTS
- who: Phoebe Dace and Gregory M. Findlay from the (UNIVERSITY) have published the research work: Reducing uncertainty in genetic testing with Saturation Genome Editing, in the Journal: (JOURNAL)
- what: Crucially, this analysis revealed the assay to be highly accurate independent of variant type (e. g., nonsense, missense, synonymous, intronic), owing to the fact variants were edited into the human genome with CRISPR.
- how: The key to a successful MAVE is being able to quantify each specific variant`s effect with NGS such that all variants can be tested in a pooled format thereby . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.