HIGHLIGHTS
- who: Xinhui Wang and collaborators from the Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, China have published the research work: Reduction-Hypersensitive Podophyllotoxin Prodrug Self-Assembled Nanoparticles for Cancer Treatment, in the Journal: Pharmaceutics 2023, 784 of /2023/
- what: Three novel Fmoc-PPT prodrugs were designed by utilizing different lengths of disulfide bonds.
SUMMARY
Only using the nano delivery strategy to deliver highly toxic chemotherapeutic drugs may cause more serious damage to normal organs and tissues due to the prolonged retention time in_vivo. The three prodrug NPs . . .
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