Reduction of advanced-glycation end products levels and inhibition of rage signaling decreases rat vascular calcification induced by diabetes

HIGHLIGHTS

  • who: Mathieu R. Brodeur. et al. from the Faculty of Pharmacy, Université de Montréal, Montréal, Québec, CanadaEditor: Tim DOury, University of Pittsburgh, United States of America have published the research: Reduction of Advanced-Glycation End Products Levels and Inhibition of RAGE Signaling Decreases Rat Vascular Calcification Induced by Diabetes, in the Journal: PLOS ONE | www.plosone.org of January/21,/2014
  • what: This study was designed to determine if AGEs are essential for the development of arterial calcification in diabetes and if RAGE signaling plays an important role in that pathological process . . .

     

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