Reduction of blood pressure, plasma cholesterol, and atherosclerosis by elevated endothelial nitric oxide*

HIGHLIGHTS

  • who: Rien van Haperen from the (UNIVERSITY) have published the research work: Reduction of Blood Pressure, Plasma Cholesterol, and Atherosclerosis by Elevated Endothelial Nitric Oxide*, in the Journal: (JOURNAL) of September/16,/2002
  • what: This study shows that the construct results in high level expression of human eNOS that is not prevented by a feedback mechanism.
  • how: In the first part of the study the authors used 12 eNOS-Tg2 and 5 eNOS-Tg3 mice for screening of eNOS expression and compared them to 33 wild_type mice. Effect of L-NAME on Systemic . . .

     

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