Reference-free lossless compression of nanopore sequencing reads using an approximate assembly approach

HIGHLIGHTS

• who: Qingxi Meng from the DepartmentStanford University have published the research work: Reference-free lossless compression of nanopore sequencing reads using an approximate assembly approach, in the Journal: Scientific Reports Scientific Reports
• what: The authors compare NanoSpring to the current state-of-the-art reference-free compressors for nanopore FASTQ files, u00adENANO6 and u00adCoLoRd10 and to pigz (https://u200bzlib.u200bnet/u200bpigz/) which is a multithreaded version of the general-purpose compressor Gzip. For each potentially matching read obtained using MinHash, the authors attempt to align it to the consensus_sequence using the minimap2 au00ad ligner7. The . . .
  

   

  

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