Regenerating zebrafish fin epigenome is characterized by stable lineage-specific dna methylation and dynamic chromatin accessibility

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  • who: Hyung Joo Lee from the All zebrafish were used in accordance with the protocols approved by the Washington University Animal Studies Committee (Protocol #20130107)Wildtype TU, AB, Tg(sp7:EGFP) [29], and Tg(hsp70:zCas, have published the paper: Regenerating zebrafish fin epigenome is characterized by stable lineage-specific DNA methylation and dynamic chromatin accessibility, in the Journal: (JOURNAL)
  • what: The study shows that lineage-specific signatures are stably maintained during regeneration and regeneration enhancers are preset as hypomethylated before injury. With this rationale, the authors reason that the DNA methylation signatures defining cell . . .

     

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