Regioselective ni-catalyzed reductive alkylsilylation of acrylonitrile with unactivated alkyl bromides and chlorosilanes

HIGHLIGHTS

  • who: Jinwei Sun from the (UNIVERSITY) have published the research work: Regioselective Ni-Catalyzed reductive alkylsilylation of acrylonitrile with unactivated alkyl bromides and chlorosilanes, in the Journal: (JOURNAL) of 10/Nov/2022
  • what: The authors report an approach for synthesizing organosilicon compounds, and present a straightforward way to access alkylsilanes bearing versatile structural complexity. Reaction development To initiate the study , the authors chose (3-bromopropyl)benzene (1a) as the carbon electrophile, acrylonitrile (2a) as the alkene unit, and chlorodimethyl(vinyl)silane (3a) as the silyl electrophile to investigate the optimal conditions. This approach provides a . . .

     

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