Regorafenib induces senescence and epithelial-mesenchymal transition in colorectal cancer to promote drug resistance

HIGHLIGHTS

  • who: Pashalina Kehagias and collaborators from the Laboratory of Clinical and Experimental Oncology, Institut Jules Bordet, Universitu00e9 Libre de Bruxelles (ULB) have published the article: Regorafenib Induces Senescence and Epithelial-Mesenchymal Transition in Colorectal Cancer to Promote Drug Resistance, in the Journal: Cells 2022, 11, x FOR PEER REVIEW of /2022/
  • what: The authors explored the effects of short and long-term regorafenib exposure on representative human CRC cell lines to identify resistance mechanisms to this MKI. 8 of 20 Following these indications, the authors aimed to identify changes in the proportion of cells in . . .

     

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