HIGHLIGHTS
- who: Yu-Chan Chang from the (UNIVERSITY) have published the article: Regorafenib inhibits epithelial-mesenchymal transition and suppresses cholangiocarcinoma metastasis via YAP1-AREG axis, in the Journal: (JOURNAL) of 31/08/2021
- what: The authors investigated the role of YAP1 in the occurrence and regulation of metastasis of CCA. The authors propose that YAP1 is an important transcription factor for CCA tumorigenesis and is inhibited by regorafenib. The authors demonstrated that regorafenib could inhibit EMT through the YAP1 pathway.
- how: All animal experiments were conducted in accordance with a protocol approved by the . . .
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