Regulation of arginine acquisition and virulence gene expression in the human pathogen streptococcus pneumoniae by transcription regulators argr1 and ahrc

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• who: Tomas G. Kloosterman from the Tomas GKloosterman, and Oscar P. Kuipers, From the Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh, AG Groningen, The Netherlands Background: Arginine is a key amino acid in cellular metabolism in bacteria. Results: Arg, and AhrC mediate arginine-dependent expression of arginine acquisition and virulence genes in the human pathogen Streptococcus pneumoniae. Conclusions: Arginine regulation in S. pneumoniae significantly differs from that in other model bacteria. Significance: Understanding metabolic regulation increases insights into the molecular pathogenesis of S. pneumoniae. In this study, we investigated for . . .
  

   

  

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