HIGHLIGHTS
- who: Epstein-Barr virus nuclear antigens and colleagues from the School of Life Sciences, University of Sussex, Brighton , QG, UK have published the article: Regulation of B cell receptor signalling by Epstein - Barr virus nuclear antigens, in the Journal: (JOURNAL) of 30/Oct/2022
- what: The authors show that the EBV transcription factors EBNA2, 3A, 3B and 3C bind to genomic sites around multiple B cell receptor (BCR) pathway genes, regulate their expression and affect BCR signalling. Studying repression of CD79B, the authors show that EBNA2 decreases transcription by disrupting binding of Early B cell . . .
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