HIGHLIGHTS
- who: Ya-fang Wang from the (UNIVERSITY) have published the research work: Regulation of CCL2 by EZH2 affects tumor-associated macrophages polarization and infiltration in breast cancer, in the Journal: (JOURNAL) of 22/03/2022
- what: The authors focused on exploring the role of EZH2 inhibitors in TAMs differentiation in this study, which may influence the efficacy of EZH2 inhibitors against breast cancer. The regulation of tumor-macrophage interactions by EZH2-miR-124-3p-CCL2 axis as uncovered in the study demonstrated that blockade of cytokines not only had direct intrinsic inhibitory effect on tumor . . .
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