HIGHLIGHTS
- who: Curtis Bradney from the (UNIVERSITY) have published the research: Regulation of E2A Activities by Histone Acetyltransferases in B Lymphocyte Development*, in the Journal: (JOURNAL) of November/11,/2002
- what: The authors show that these HATs acetylate E2A in_vitro, enhance E2A-mediated transcription activity, and promote nuclear retention of E2A proteins. The authors provide biochemical and genetic evidence to show that the HATs p300, CBP, and PCAF are regulators of E2A activity in B lymphocytes and the regulation is important for proper B cell development. In the same tests, the authors show that GST-p53 . . .
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