Regulation of epitope exposure in the gp41 membrane-proximal external region through interactions at the apex of hiv-1 env

HIGHLIGHTS

  • who: Hannah M. Schapiro and colleagues from the University, Philadelphia, Pennsylvania, United States of America, Department of Microbial Infection and have published the research work: Regulation of epitope exposure in the gp41 membrane-proximal external region through interactions at the apex of HIV-1 Env, in the Journal: (JOURNAL) of May/18,/2022
  • what: As the sole viral protein on the virion surface, Env is the primary focus of vaccine development efforts to generate neutralizing antibodies (NAbs) that block viral_replication . The authors further investigated the regulation of this conformational flexibility by exploring how inter- and . . .

     

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