Regulation of htlv-1 tax stability, cellular trafficking and nf-κb activation by the ubiquitin-proteasome pathway

HIGHLIGHTS

• who: Alfonso Lavorgna and Edward William Harhaj * from the Department of Oncology, Sidney Kimmel Comprehensive Cancer Center have published the research: Regulation of HTLV-1 Tax Stability, Cellular Trafficking and NF-κB Activation by the Ubiquitin-Proteasome Pathway, in the Journal: Viruses 2014, 6, 3925-3943 of 15/Oct/2014
• what: The authors declare no conflict of interest.

SUMMARY

Productively infected HTLV-1+ cells establish a virological synapse by cell-cell contact with uninfected T_cells mediated by interactions between ICAM-1 and LFA-1 adhesion molecules. The virological synapse mediates the . . .

 



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