Regulation of microglia related neuroinflammation contributes to the protective effect of gelsevirine on ischemic stroke

HIGHLIGHTS

  • who: Chunlei Xing from the Shanghai University (Approval NOECSHU2021-167) and reportedUniversity, United States have published the research: Regulation of microglia related neuroinflammation contributes to the protective effect of Gelsevirine on ischemic stroke, in the Journal: (JOURNAL)
  • what: The authors investigated the protective effects of Gs on stroke and potential mechanisms.
  • how: These results indicated that the administration of Gs decreased neuroinflammation by the down-regulation of inflammatory cytokines in_vitro and in_vivo.

SUMMARY

    Effect on microglia in_vitro models mRNA transcription of cytokines was analyzed by quantitative reverse-transcription polymerase_chain_reaction . . .

     

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