HIGHLIGHTS
- who: NADPH oxidase (NOX et al. from the UCONN Health, United States University of Rochester, United States have published the research work: Regulation of Neutrophil NADPH Oxidase, NOX2: A Crucial Effector in Neutrophil Phenotype and Function, in the Journal: (JOURNAL)
- how: The following model can be proposed the complex assembly occurs as soon as the phagocytosis starts then p47phox and Rac2 leave the phagosome within a few minutes whereas p40phox and p67phox stay until the end of ROS production .
SUMMARY
Recent data indicate that CGD neutrophils have an increased cytokine production . . .
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