Regulation of nmda receptor signaling at single synapses by human anti-nmda receptor antibodies

HIGHLIGHTS

• who: David R. Benavides from the Department of Neurology, University of Maryland School of Medicine, Baltimore, MD, United States, Department have published the research: Regulation of NMDA Receptor Signaling at Single Synapses by Human Anti-NMDA Receptor Antibodies, in the Journal: (JOURNAL)
• what: The authors demonstrate critical functions of synaptic NMDARs are not disrupted by GluN1 antibodies using a combination of immunohistochemical and live-cell imaging techniques in neuron cultures.
• future: Future studies should explore whether the effects described here are reproduced with other GluN1 clones mixtures of clones patient CSF or pathogenic . . .
  

   

  

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