Regulation of the interaction between protein kinase c-related protein kinase 2 (prk2) and its upstream kinase, 3-phosphoinositide-dependent protein kinase 1 (pdk1)*

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  • who: Rosalia Dettori from the (UNIVERSITY) have published the research: Regulation of the Interaction between Protein Kinase C-related Protein Kinase 2 (PRK2) and Its Upstream Kinase, 3-Phosphoinositide-dependent Protein Kinase 1 (PDK1)*, in the Journal: (JOURNAL) of October/30,/2009
  • what: The results of this analysis showed that in PRK2 and PKC␨ two sites were phosphorylated in_vivo: (i) the activation loop site (Thr-816 in PRK2) and_(ii) the Z/TM site (Thr-958 in PRK2; depicted in Fig 1A).
  • how: The results showed that the hydrophobic patch (Ile-965/Leu . . .

     

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