Regulation of the uncoupling protein-2 gene in ins-1 ù²-cells by oleic acid*

HIGHLIGHTS

  • who: Alexander V. Medvedev from the (UNIVERSITY) have published the research work: Regulation of the Uncoupling Protein-2 Gene in INS-1 Ù²-Cells by Oleic Acid*, in the Journal: (JOURNAL) of August/22,/2002
  • what: The authors show that UCP2 mRNA and protein levels were increased after a 48-h exposure of INS-1(832/13) ␤-cells to oleic acid (0.5 mM) by activation of the UCP2 promoter. The authors investigated the target elements for FFA-dependent regulation of the UCP2 promoter in the pancreatic ␤-cell line INS-1(832/13). The authors show . . .

     

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