Regulation of transient receptor potential canonical 4 activity by phospholipase c-δ1

HIGHLIGHTS

• who: Juyeon from the Department of Physiology, Seoul National University College of Medicine, Seoul, Republic of Seattle, WA, USA have published the research: Regulation of Transient Receptor Potential Canonical 4 Activity by Phospholipase C-δ1, in the Journal: (JOURNAL)
• what: Altogether, the authors propose a negative_feedback regulation of TRPC4 by PLCδ1 in calcium and PIP2 dependent manner. The authors provide an evidence that PLCδ1 directly interact with TRPC4β based on the results of FRET and Co-IP experiments (Fig 1).
• how: TRPM8 neurons express Ca2+-sensitive PLCδ isozymes28 and in_vivo data . . .
  

   

  

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