HIGHLIGHTS
- who: Archittapon Nokkeaw and collaborators from the Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand have published the research: Regulatory Functions and Mechanisms of Circular RNAs in Hepatic Stellate Cell Activation and Liver Fibrosis, in the Journal: Cells 2023, 378 of /2023/
- what: This study shows that circMTM1 knockdown expression and miR-122-5p overexpression reduce the expression levels of activated HSC markers, while the upregulation of IL7R attenuates the anti-fibrotic function of miR-122-5p .
- future: Investigations are needed to expand the knowledge of how the circSMYD4/miR-660 . . .
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