HIGHLIGHTS
- who: Kamira Maharaj from the Osaka University, Japan have published the paper: Regulatory T cells (Tregs) in lymphoid malignancies and the impact of novel therapies, in the Journal: (JOURNAL)
- what: The studies discussed in this section indicate that Tregs harbor altered surface markers Frontiers in Immunology frontiersin.org 10.3389/fimmu.2022.943354 characterized by altered transcriptional and cytokine profiles when compared to healthy donors . This study demonstrated that isolated CLL-derived Tregs killed CLL cells in ex vivo assays, indicating the potential to eliminate malignant cells . The study showed that IL-10 signaling was . . .
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