Reinventing the human tuberculosis (tb) granuloma: learning from the cancer field

HIGHLIGHTS

  • who: Senait Ashenafi from the Southwest, China have published the article: Reinventing the human tuberculosis (TB) granuloma: Learning from the cancer field, in the Journal: (JOURNAL)

SUMMARY

    A central role of both conventional and unconventional CD4+ and CD8+ T_cells have been described in TB infection and cancer including complementary as well as overlapping functions of CD4+ and CD8+ T_cells. CD4+ T_cells are considered mandatory to support activation of other immune cells such as macrophages, CD8+ T_cells and B cells by production of Th1 effector cytokines IFN-g and TNF-a. Under specific circumstances . . .

     

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