Relationship between homodimeric glucocorticoid receptor and transcriptional regulation assessed via an in vitro fluorescence correlation spectroscopy-microwell system

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  • who: from the (UNIVERSITY) have published the article: Relationship Between Homodimeric Glucocorticoid Receptor and Transcriptional Regulation Assessed via an In Vitro Fluorescence Correlation Spectroscopy-Microwell System, in the Journal: (JOURNAL) of 25/08/2017
  • what: The authors determined the concentration of GR homodimer, and its dissociation_constant (Kd), at the single-cell level, by using fluorescence correlation spectroscopy (FCS) combined with a microwell system.
  • how: This result was consistent with a previous study which identified GR homodimerization at high concentrations under uninduced conditions and monomeric GR at low concentrations33. The authors used an in_vitro . . .

     

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