Relationship between lysine methyltransferase levels and heterochromatin gene repression in living cells and in silico

HIGHLIGHTS

• who: Xiaokang Yan from the Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, USA have published the article: Relationship between lysine methyltransferase levels and heterochromatin gene repression in living cells and in silico, in the Journal: (JOURNAL)
• what: For the focus of this work, histone protein modification state is passed on from generation to generu00ad ation as a form of epigenetic_information. The authors knocked down SETDB1 using a dCas9-KRAB repression system and examined the changes . . .
  

   

  

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