Relationship between mitochondrial structure and bioenergetics in pseudoxanthoma elasticum dermal fibroblasts

HIGHLIGHTS

  • who: Daniela Quaglino from the Department of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy, Department of Human Physiology have published the paper: Relationship Between Mitochondrial Structure and Bioenergetics in Pseudoxanthoma elasticum Dermal Fibroblasts, in the Journal: (JOURNAL)
  • what: Although this study was performed on a limited number of cases, the use of integrated technical approaches (i.e., proteomic, biochemical, and morphological analyses) revealed that PXE fibroblasts grown in standard medium were characterized by a peculiar protein signature consistent with altered mitochondrial structure and bioenergenetics.
  • how: Data were analyzed using GraphPad . . .

     

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