Relaxin as a therapeutic target for the cardiovascular complications of diabetes

HIGHLIGHTS

  • who: Hooi Hooi Ng from the School of BioSciences, The University of Melbourne, Melbourne, VIC, Australia, Heart Failure, Baker Heart have published the Article: Relaxin as a Therapeutic Target for the Cardiovascular Complications of Diabetes, in the Journal: (JOURNAL)
  • what: The authors propose a small peptide hormone, relaxin, which shows a promising role in protecting the cardiovascular system (Leo et_al, 2016a; Sarwar et_al, 2017).

SUMMARY

    Hyperglycemia leads to the imbalance of vasoprotective molecules such as nitric oxide (NO), prostacyclin (PGI2 ), and endothelium-derived hyperpolarization (EDH) pathways, and causes overproduction of ROS . . .

     

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