Relb contributes to the survival, migration and lymphomagenesis of b cells with constitutively active cd40 signaling

HIGHLIGHTS

  • who: Laura B. Kuhn from the University of Erlangen Nuremberg, Germany have published the article: RelB contributes to the survival, migration and lymphomagenesis of B cells with constitutively active CD40 signaling, in the Journal: (JOURNAL)
  • what: The approach has the advantage that the authors can learn how RelB contributes to gene regulation and lymphomagenesis.
  • how: Were evaluated using FlowJo (TreeStar). continuous CD40-stimulation of lymphoma cells contributes to lymphoma cell survival proliferation and drug resistance . The following mice were analyzed LMP1/CD40stopfl//CD19-Cre+/(LMP1/CD40) LMP1/CD40 stopfl //RelB fl/fl //CD19 . . .

     

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