Release of neuronal hmgb1 by ethanol through decreased hdac activity activates brain neuroimmune signaling

HIGHLIGHTS

• who: Signaling et al. from the Bowles Center For Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America have published the research work: Release of Neuronal HMGB1 by Ethanol through Decreased HDAC Activity Activates Brain Neuroimmune Signaling, in the Journal: PLOS ONE | www.plosone.org of February/14,/2014
• what: This study investigated the mechanisms for ethanol-induced release of HMGB1 and neuroimmune activation in a model of rat hippocampal-entorhinal cortex (HEC) brain slice cultures. The authors report here that HMGB1 appears to be highly expressed . . .
  

   

  

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