HIGHLIGHTS
- who: Luca Massacesi et al. from the Department of Neurosciences, Drug and Child Health, University of Florence, Florence, Italy have published the article: Relevance of Pathogenetic Mechanisms to Clinical Effectiveness of B-Cell-Depleting Monoclonal Antibodies in Multiple Sclerosis, in the Journal: (JOURNAL)
SUMMARY
Circulating CD4+ T_cells from MS patients were indeed demonstrated to recognise myelin basic protein (MBP), proteolipid protein (PLP), and myelin oligodendrocyte glycoprotein (MOG), even if the same phenomenon was also observed in healthy individuals; evidence regarding potential differences between these groups in frequency and avidity of cell interactions is . . .
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