Remodeling of the histoplasma capsulatum membrane induced by monoclonal antibodies

HIGHLIGHTS

  • who: Meagan C. Burnet and colleagues from the Department of Microbiology and Immunology and Division of Infectious Diseases, Department of Medicine have published the research work: Remodeling of the Histoplasma Capsulatum Membrane Induced by Monoclonal Antibodies, in the Journal: Vaccines 2020, 8, 269 of 15/08/2016
  • what: The authors studied the cellular effects of HSP60-binding mAbs 6B7 and 7B6 to H. capsulatum yeast cells by a multi-omics approach.
  • how: The authors also showed that global changes in the lipid profiles resulted in an increased susceptibility of H. to the ergosterol . . .

     

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