Renal endothelial cytotoxicity assay to diagnose and monitor renal transplant recipients for anti-endothelial antibodies

HIGHLIGHTS

  • who: Rosa G. M. Lammerts from the University of California, Los Angeles, United States have published the article: Renal Endothelial Cytotoxicity Assay to Diagnose and Monitor Renal Transplant Recipients for Anti-Endothelial Antibodies, in the Journal: (JOURNAL)

SUMMARY

    The presence of donor-specific human leukocyte antigen (HLA) antibodies in patients awaiting a renal transplant can either be a contraindication for transplantation or pose an increased risk for antibody-mediated rejection (ABMR) and inferior graft survival. This might be explained by HLA-specific memory cells that become activated upon re-exposure to the antigen . . .

     

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