Renal oncometabolite l-2-hydroxyglutarate imposes a block in kidney tubulogenesis: evidence for an epigenetic basis for the l-2hg-induced impairment of differentiation

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  • who: Mary Taub from the Harvard Medical School, United States Washington University in StLouis have published the Article: Renal oncometabolite L-2-hydroxyglutarate imposes a block in kidney tubulogenesis: Evidence for an epigenetic basis for the L-2HG-induced impairment of differentiation, in the Journal: (JOURNAL)
  • what: The authors examine the hypothesis that elevated 2HG affects the differentiation of normal renal cells, altering their ability to undergo tubulogenesis. Blots used in the study were prepared following Western transfers of SDS/PAGE gels, as described in Materials and Methods. The studies with primary RPT_cells treated with . . .

     

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