HIGHLIGHTS
- who: Sophie Howarth from the Translational and Clinical Research Institute, Newcastle University, Newcastle-upon-Tyne, RU, UK have published the article: Replication of association at the LPP and UBASH3A loci in a UK autoimmune Addison`s disease cohort, in the Journal: (JOURNAL)
- what: The authors demonstrate that two SNPs in the LPP gene (LIM domain containing preferred translocation partner in lipoma), rs4686484 and rs12634152, are significantly associu00ad ated with AAD.
- future: Studies with larger patient cohorts are required to robustly confirm the association of SH2B3 and SIGLEC5/SPACA6 alleles.
SUMMARY
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