HIGHLIGHTS
- who: Ke Liu from the (UNIVERSITY) have published the article: Reprogramming the tumor microenvironment by genome editing for precision cancer therapy, in the Journal: (JOURNAL)
- what: Currently, gene editing is mainly used to reprogram TAFs, which are the main focus of the discussion . Immune escape mediated by immune checkpoints is recognized as one of the main reasons.
- how: The results showed that these cells exhibited restored cytotoxicity and killing ability specific for tumor cells .
SUMMARY
The primary target cells for gene editing in the TME are T_cells, natural killer . . .
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