Reprogramming tumor-associated macrophages as a unique approach to target tumor immunotherapy

HIGHLIGHTS

• who: Safir Ullah Khan from the Universitu00e9 Sorbonne Paris Nord, France University of Michigan, United States have published the article: Reprogramming tumor-associated macrophages as a unique approach to target tumor immunotherapy, in the Journal: (JOURNAL)

SUMMARY

While M1-like tumor-associated macrophages (M1-TAMs) predominate early in tumor development, M2-like tumor-associated macrophages (M2TAMs) take over in the tumor`s intermediate and late stages, where they can increase angiogenesis, aid in tumor cell dissemination and metastasis, and have a pro-tumor effect. Consequently, metabolic reprogramming of M2-like TAMs, preventing the . . .

 



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